SkinPen® Precision Indications
SkinPen® Precision Microneedling System is a medical device intended to treat facial acne scars in adults aged 22 years or older. SkinPen® Precision Microneedling System is also intended to help improve the cosmetic appearance of fine lines, wrinkles, stretch marks, surgical scars, enlarged pores and pigmentation conditions (dyschromia).
Mottled Hyperpigmented Lesions/Patches
- A common skin condition with an unknown exact cause.
- It is associated with both sun exposure and hormonally activated melanocytes, which cause an uneven increase in facial melanin by stimulating melanocyte-stimulating hormone (MSH).
- Although more common in individuals with higher pigmentation, it can affect all skin types.
V. Sheth et al, JAAD (2010) https://doi.org/10.1016/j.jaad.2010.12.046
Mechanism of Action:
- Stimulates keratinocyte turnover and helps “restore” normal pigment activity in melanocytes within hyperpigmented areas.
- This process takes place at the dermal-epidermal junction (DEJ).
- The DEJ and shallow dermis are the targeted depths for microneedling, where microchannels are formed (as indicated by arrows).
Cassiano et al., Indian Journal of Dermatology, Venereology and Leprology | Volume 85 | Issue 6 | November-December 2019
Epidermal melanin density in melasma before procedure
Reduction in epidermal melanin density 1 week after microneedling procedure
