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The BELOTERO® Portfolio

The BELOTERO® Collection brings together seven carefully developed products, each with its own unique characteristics. As part of one integrated portfolio, they provide healthcare professionals with the flexibility to create personalized treatment plans while maintaining a consistent approach to patient care and aesthetic outcomes.

BELOTERO® Balance

Smooth integration for refined corrections.

BELOTERO® Balance is designed for the correction of moderate lines and folds while maintaining a natural look and feel. Thanks to CPM® technology, the gel integrates seamlessly into the tissue, making it a versatile choice for wrinkle correction, contour refinement, and lip enhancement.

Treatment areas: Nasolabial folds • Marionette lines • Perioral lines • Oral commissures • Lip contours • Lip enhancement

Level of injection: Mid to deep dermis. For lip treatments: submucosal injection.

BELOTERO® Intense

Enhanced projection and structural support.

BELOTERO® Intense is developed for deeper lines, facial definition, and volume enhancement. With its higher elasticity and viscosity, it provides strong lifting capacity and projection while maintaining smooth integration and natural-looking outcomes

Treatment areas: Nasolabial folds • Marionette lines • Perioral lines • Oral commissures • Lip contours • Lip enhancement

Level of injection: Mid to deep dermis. For lip treatments: submucosal injection.

BELOTERO® Soft

Delicate correction for fine lines.

BELOTERO® Soft is specifically developed for the treatment of superficial lines and early signs of aging. Its soft, cohesive gel integrates smoothly into the skin, providing subtle correction and refreshed appereance while maintaining natural facial expression.

Treatment areas: Crow’s feet • Perioral lines • Fine facial lines

Level of injection: Superficial to mid-dermis.

 

BELOTERO® Volume

Restoring Volume with confidence. 

BELOTERO® Volume is specifically developed to restore facial volume and support contour definition in areas affected by age-related volume loss. Its tailored plasticity, cohesivity and lifting capacity help create harmonious facial contours while maintaining natural-looking results.

Treatment ares: Cheeks • Cheekbones • Temples

Level of injection: Deep subcutaneous and supra-periosteal

BELOTERO® Revive

Hydration from within. Radiance from the surface.

BELOTERO® Revive is specifically designed to improve overall skin quality through deep hydration and revitalization. Combining hyaluronic acid with glycerol, it helps improve skin elasticity, firmness, and smoothness while reducing the appearance of fine lines and signs of skin aging.

Treatment ares: Cheeks • Lower cheeks • Fine lines • Aging skin • Skin quality improvement

Level of injection: Mid to deep dermis.

BELOTERO® Lips Contour

Precise definition for beautifully refined lips.

BELOTERO® Lips Contour is specifically developed to enhance and restore lip contours while preserving a natural appearance. Designed for precise definition of the vermillion border and surrounding lip area, it helps create well-defined, balanced lips and a more youthful look.

Treatment areas: Lip contours • Vermillion border • Cupid’s bow • Perioral lines • Oral commissures

Level of injection: Lip enhancement: submucosal or subcutaneous injection. Lip contour, perioral lines and oral commissures: superficial to mid-dermis.

BELOTERO® Lips Shape

Volume designed for beautiful proportions. 

BELOTERO® Lips Shape is specifically developed to enhance lip volume and support fuller, well-balanced lips. With its high elasticity and viscosity, it provides projection, structure and volume while maintaining natural movement and expression.

Treatment areas: Lip augmentation • Lip volume enhancement • Oral commissures

Level of injection: Lips: subcutaneous or submucosal injection

 

References

  1. Casabona G, et al. Tissue-Plane Adaptability of Hyaluronic Acid Gels. Dermatologic Surgery. 2026
  2. Patent Note: WO 2005/085329 “Biocompatible crosslinked gel„
  3. BELOTERO® Balance. Instructions for Use. 2026
  4. BELOTERO® Soft. Instructions for Use. 2025
  5. BELOTERO ® Intense. Instructions for Use. 2025
  6. BELOTERO ® Volume. Instructions for Use. 2025
  7. BELOTERO ® Revive, Instructions for Use. 2025
  8. Kerscher M, Prager W. Fischer TC, et al. Facial S. Plastic and Reconstructive Surgery-Global Open. 2021
  9. Kühne U, Esmann J, von Heimburg D, Imhof M, Weissenberger P, Sattler G. Safety and performance of cohesive polydensified matrix hyaluronic acid fillers with lidocaine in the clinical setting – an open-label, multicenter study, Clin Cosmet Investig Dermatol. 2016
  10. Casabona G, et al. Tissue-Plane Adaptability of Hyaluronic Acid Gels. Dermatologic Surgery. 2026
  11. Merz Aesthetics. Data on Files. 2025.
  12. Kerscher M, Prager W, Fischer TC, et al. Facial S. Plastic and Reconstructive Surgery-Global Open. 2021:9(12):e3973.
  13. Kühne U, Esmann J, von Heimburg D, Imhof M, Weissenberger P, Sattler G. Clin Cosmet Investig Dermatol. 2016;9:373-81.
  14. Vandeputte J.J Clin Aesthet Dermatol. 2018 Dec;11(12):30-39.
  15. Hertz-Kleptow D, Hanschmann A, Hofmann M, et al. Facial skin revitalization with CPM-HA20G: an effective and safe early intervention treatment. Clin Cosmet Investig Dermatol. 2019a;12:563-72.
  16. Moradi et al. 2024. JDD
  17. van Loghem J et al. Clin Cosmet Investig Dermatol. 2021;14:1175–1199.
  18. Wollina et al. Dermatologic Therapy. 2021;e15045
  19. Suwanchinda A, et al. J Cosmet Dermatol. 2026;25(3):e70784. ​