Radiesse is an injectable dermal filler that temporarily adds volume to help smooth moderate to severe facial wrinkles and gives an immediate lifting and firming effect of the skin. Once injected, Radiesse directly provides volume and lift needed to diminish the signs of ageing because of the calcium-based microspheres and gel that comprise the product. The unique formulation of Radiesse stimulates the production of new collagen, which results in increased volume that may last a year or more in many patients.

Radiesse is able to provide the volume and lift needed to reduce the signs of ageing, thanks to its calcium-based microspheres and gel. Over time, both the gel and the microspheres are completely broken down by the body via the body’s natural metabolism. The calcium and phosphates that are released are identical to the body’s own minerals.

As well as having an immediate volumising effect, Radiesse’s CaHA microspheres (Calcium Hydroxylapatite) stimulate the skin’s natural collagen synthesis. Thanks to the collagen-inducing effect of Radiesse, the skin regains its youthful tightness and elasticity.

Radiesse offers

  • Immediate correction of moderate to severe wrinkles
  • Immediate lifting and contouring effects
  • Stimulates the production of the skin’s natural collagen
  • Long-term improvement of skin quality
  • Feels soft and looks natural
  • Provides results that last a year or more in many patients
  • Allows for an easy and convenient treatment

How does Radiesse work and how is it injected?

Radiesse adds instant fill by smoothing moderate to severe facial wrinkles, and both lifts and firms the skin. It provides an instant one-to-one correction and with just one injection, many patients experience an immediate and longlasting youthful appearance. Radiesse is carefully injected by the practitioner into the skin, usually in small quantities with a very fine needle.

As well as having a volumising effect, Radiesse also stimulates the skin cells’ regeneration process. Compared with hyaluronic acid, the skin’s regeneration process is significantly higher after a CaHa injection.

Injections with CaHA microspheres effectively stimulate collagen production. Within a period of 3-12 months, a single injection of Radiesse results in a comprehensive network of newly formed type I collagen, compared with HA. The skin’s elasticity is also significantly increased, and compared with HA, Radiesse demonstrates a higher quantity of intact elastin.

After the injection, Radiesse adds instant volume and correction while stimulating the skin to produce its own natural collagen. The filler is absorbed over time; the body breaks down the CaHa microspheres and leaves the body with the skin’s natural collagen.

Get a treatment with Radiesse

Radiesse can be used for both single treatment areas and for full facial correction. As well as having an uplifting and contouring effect, Radiesse also significantly improves the quality of the skin.

See results from a full facial correction treatment in the gallery below.

Radiesse can also be used on separate areas of the face, such as the nasolabial lines, marionette lines, sunken jowls, jaw line, lower jaw and hands. See the results in the gallery below.

Radiesse contains CaHA microspheres, which are found in hydrous carboxymethyl cellulose carriers. This is one of the strongest and most uplifting contouring fillers for a deep volumising fill, which has a special stimulatory effect.

Compared with ordinary hyaluronic acid fillers, Radiesse has the highest elasticity and viscosity. The high elasticity in the Radiesse filler means it is resistant to effects from e.g. the facial musculature and gravity, giving a very stable result. The high viscosity means the filler remains at the injection point, thus giving the best shape. Radiesse is therefore particularly suitable for treating facial zones that have a high amount of movement / facial expression, or which require very precise corrections, such as the nasolabial folds and the middle and lower parts of the face.

1. Effect

Once injected, Radiesse® shows an immediate one-to-one correction and lifting effect. It can instantly soften your smile lines, replace lost volume in your cheeks, or contour your jawline.

2. Effect

Over the following weeks, Radiesse® microspheres stimulate the skin to produce new collagen for a soft, natural look.

Collagen (net)

Newly formed collagen surrounds the microspheres. The microspheres are eventually metabolised by the body’s normal processes.

3. Effect

The new collagen provides a long-term effect that may last for a year or more in many patients.

Frequently Asked Questions

If you want to know more about getting a treatment with Radiesse, you will find the frequently asked questions down below. Click on the question to see the answer.

What is Radiesse?

Radiesse is an injectable wrinkle filler that works by immediately restoring facial volume to smooth out the signs of ageing. Once injected, not only does it immediately add volume but over time, Radiesse begins to stimulate the production of the body‘s natural collagen for results that may last up to a year or more in many patients.

Is Radiesse tested and certified?

Yes, Radiesse® achieved CE certification in 2003. The CE certification is the European Union standard for product safety. Radiesse was also approved by the FDA (the American regulatory authority) in 2006.

What is the treatment procedure?

Your practitioner will explain the treatment options available and discuss with you the best one for you. Typically one treatment session takes approximately 30 minutes. The effect will be visible immediately after injection.

What if I am taking medication?

Please inform your practitioner before treatment if you are taking medication, even if it is not a prescription medicine. Taking anticoagulants and painkillers including aspirin and some vitamin supplements can lead to unwanted bruising. Your practitioner will advise you accordingly.

Are there any side effects?

You may experience some reaction to the injections. There may be mild swelling, pain, itching, bruising or discolouration, and sensitivity to pain. However, this usually disappears after a few days. Please discuss this with your practitioner.

How long does the effect of Radiesse last?

Individual results are dependent on age, skin type, lifestyle, and metabolism and, of course, the area treated. Generally, the effect of the treatment lasts over a year for most patients.

Can Radiesse be combined with other products?

For a holistic treatment of individual folds and selected areas of the face, it may be advisable to combine Radiesse with other dermal fillers. Please ask your practitioner about the Merz Aesthetics Beauty Edition, which is created specifically for a gentle lifting.

Can Radiesse be felt under the skin?

You will probably feel the material for a short time after treatment. Over time, the material is completely integrated and cannot be felt anymore.

How can I learn more about Radiesse?

Please talk to your practitioner or visit our website www.radiesse.eu

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Get a treatment with Radiesse

Are you considering getting a treatment with Radiesse? Contact your nearest retailer for more information.

Do you know Merz Institute of Advanced Aesthetics?

Merz Institute of Advanced Aesthetics (MIAA) is an online e-learning program where you can develop and optimize your skills and knowledge in the aesthetic field; from modules dealing with facial anatomy, aging and clinical practices to modules about Merz’ portfolio of products. MIAA also offers CME certified courses.


As a division of the Merz Pharma Group, Merz Aesthetics is one of the world’s leading aesthetics companies. Healthcare professionals in more than 90 countries use Merz’ products. They offer a multifaceted portfolio of minimally invasive aesthetics treatments as well as a unique range of customer services and professional training. Building on more than a century of healthcare expertise, they have a clear mission: We strive to improve patients’ health, helping them live, feel and look better.

Since creating the world’s first anti-wrinkle cream in 1953, Merz has been a driver of innovation in the fast-evolving field of aesthetic medicine. Merz is a privately held pharmaceutical company based in Frankfurt, Germany, with own branches in various European countries as well as the US, Canada, Mexico, Brazil and Asia Pacific. The company is active in research, development and distribution of innovative products in the areas of aesthetic medicine and dermatology as well as in the field of neurologically induced movement disorders.