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The Science of DermaFacial

Science You Can Measure.

Préime DermaFacial is built around a science-led approach to skin management. By combining five technologies within one treatment system, the Signature Treatment has been clinically evaluated across key parameters including skin hydration, barrier function, elasticity, firmness and wrinkle visibility. Rather than relying on visual assessment alone, the clinical evaluation incorporates objective measurement technologies to document changes in the skin throughout the treatment course.

Skin Hydration

Skin moisturisation was assessed using a Corneometer, providing an instrumental measurement of changes in skin hydration throughout the study.

Skin Barrier Function

Transepidermal Water Loss (TEWL) was measured using a Tewameter as part of the evaluation of the skin barrier during the treatment course.

Skin Firmness

Changes in skin firmness were objectively evaluated using a Ballistometer, allowing the physical properties of the skin to form part of the clinical assessment.

Wrinkle Visibility

Wrinkles were assessed through 3D imaging with EOTech Evaface, supported by standardised photography using the Canfield VISIA II System.

Clinical Validation

The Signature Treatment Efficacy Study

The technologies in the Préime DermaFacial – hydradermabrasion, microdermabrasion, microcurrent, radiofrequency and ultrasound – are well established in aesthetic skincare. Clinical findings with the Préime DermaFacial support improvements in skin texture, hydration and overall skin appearance.

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Improvement in hydration

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Increase in elasticity

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Reduction in wrinkle visibility

The Bohr Effect Explained

First described in 1904 by the Danish psyiologist Christian Bohr, the Bohr effect is a natural process in the body.

Hemoglobin, the protein in red blood cells that carries oxygen, releases oxygen more easily where the surrouding tissue has a higher level of carbon dioxide and a slighty lower (more acidic) pH.

How does VibroX use it? 

VibroX combines microdermabrasion with vibration and red LED light. Together with the VibroX pod and a Préime DermaCeuticals gel (Fresh Gel or Bright Gel), it produces the Bohr effect: CO₂ microbubbles increase oxygen delivery to the skin and support skin revival.

At the same time, dull surface cells are exfoliated, helping leave skin looking renewed, clear and glowing.